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  Citation statistics : Table of Contents
   2009| July  | Volume 63 | Issue 7  
    Online since August 20, 2009

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Stress and suicidal ideas in adolescent students in Chandigarh
Priti Arun, BS Chavan
July 2009, 63(7):281-287
DOI:10.4103/0019-5359.55112  PMID:19700908
Background and Objectives: School students in India have a high stress level and high rate of deliberate self-harm. The present study was conducted to find out stress, psychological health, and presence of suicidal ideas in school students and to find out any correlation between these variables. Setting and Design: Cross-sectional study conducted on school students in urban area of Chandigarh city. Materials and Methods: Data was collected on 2402 students from classes VII to XII on socio-demographic scale, 12-item general health questionnaire, Mooney problem checklist, and suicide risk eleven -a visual analogue scale. Statistical analysis used was chi square and Spearman's correlation. Results: Out of 2402 students, 1078 (45.8%) had psychological problems, half (1201 students) perceived problems in their role as students, 930 (45%) reported academic decline, 180 (8.82%) students reported that life was a burden, 122 (6%) reported suicidal ideas and 8 (0.39%) students reported suicidal attempt. There was significant correlation between student's perception of life as a burden and class they were studying, mother's working status, psychological problems and problems students experienced in relation to study, peers, future planning and with parents. Conclusions: Students with academic problems and unsupportive environment at home perceived life as a burden and had higher rates of suicidal ideations.
  12 8,824 609
Bacterial biofilm formation, pathogenicity, diagnostics and control: An overview
Rajesh Sawhney, Vandana Berry
July 2009, 63(7):313-321
DOI:10.4103/0019-5359.55113  PMID:19700915
Bacterial biofilms are complex, mono- or poly-microbialn communities adhering to biotic or abiotic surfaces. This adaptation has been implicated as a survival strategy. The formation of biofilms is mediated by mechanical, biochemical and genetical factors. The biofilms enhance the virulence of the pathogen and have their potential role in various infections, such as dental caries, cystic fibrosis, osteonecrosis, urinary tract infection and eye infections. A number of diagnostic techniques, viz., bright-field microscopy, epifluorescence microscopy, scanning electron microscopy, confocal laser scanning microscopy and amplicon length heterogeneity polymerase chain reaction, have been employed for detection of these communities. Researchers have worked on applications of catheter lock solutions, a fish protein coating, acid shock treatment, susceptibility to bacteriophages, etc., for biofilm control. However, we need to rearrange our strategies to have thorough insight and concentrate on priority basis to develop new accurate, precise and rapid diagnostic protocols for detection and evaluation of biofilm. Above all, the strict compliance to these techniques is required for accurate diagnosis and control.
  9 16,681 1,385
Left ventricular noncompaction: A cardiomyopathy often mistaken
Jyoti C Suvarna, Chandrahas T Deshmukh, Shalini A Hajela
July 2009, 63(7):303-307
DOI:10.4103/0019-5359.55119  PMID:19700911
Left ventricular noncompaction (LVNC) is a rare genetic cardiomyopathy postulated to be a defect in endomyocardial morphogenesis due to the embryonic arrest of the compaction of myocardial fibers. It could be isolated, without other structural heart defects; or associated with congenital heart defects. It is characterized by prominent ventricular myocardial trabeculations and deep intertrabecular recesses. The clinical manifestations, i.e., heart failure, arrhythmias or thromboembolism, overlap with those of other cardiac disorders. It is often misdiagnosed as restrictive or dilated cardiomyopathy. The high mortality and morbidity associated with it and familial occurrence make diagnosis important. Only 3 pediatric cases have been reported from India. We present 2 cases, that of an 11-year-old girl (familial case) with embolism (documented but rare in children) and atrial flutter (not yet reported), with mother having asymptomatic LVNC; and that of a 4-month-old girl. Both presented with heart failure. The 11-year-old child had sudden death, known to occur in LVNC.
  5 4,925 366
Epidemiology and genetics of dilated cardiomyopathy in the Indian context
B Ushasree, V Shivani, A Venkateshwari, RK Jain, C Narsimhan, Pratibha Nallari
July 2009, 63(7):288-296
DOI:10.4103/0019-5359.55114  PMID:19700909
Background: Dilated cardiomyopathy (DCM) still remains to be a poorly understood and less analyzed group of cardiac-muscle disorders when compared to hypertrophic cardiomyopathy (HCM). Also, the vast clinical heterogeneity among the patients has rendered the small and isolated kindred studies less informative on the genetics and epidemiology of DCM. Aim of the study: The study aimed at understanding the epidemiology and genetics of DCMs in the Indian context. Materials and methods/ Statistical analysis: One hundred seven DCM patients and 105 healthy individuals were included in the study for epidemiological and genetic risk factor identification and to fit the possible mode of inheritance. Single's ascertainment methodology for segregation analysis and Penrose frequency estimates were followed to evaluate for the role of specific epidemiological factors in the disease etiology. Chi-square analysis was carried out to interpret the results statistically. Results and Conclusion: Our study suggests that epidemiological factors like gender, age at onset and vegetarian diet in conjunction with sarcomere gene mutations may play a role in the disease expression. Similarly, segregation analysis for the possible mode of inheritance showed a deviation from the autosomal dominant mode of inheritance, strengthening the underlying genetic heterogeneity of DCM.
  4 3,930 514
Detergents - uncommon household poisons
V Suri, S Mahi, A Bhalla, N Sharma, S Varma
July 2009, 63(7):311-312
DOI:10.4103/0019-5359.55115  PMID:19700914
  1 1,993 250
Understanding adolescents' suicidal ideation and attempts
Putai Jin
July 2009, 63(7):279-280
DOI:10.4103/0019-5359.55111  PMID:19700907
  - 2,179 405
Substance abuse among medical professionals: A way of coping with job dissatisfaction and adverse work environments?
Anant Bhan
July 2009, 63(7):308-309
DOI:10.4103/0019-5359.55118  PMID:19700912
  - 3,035 288
Human papilloma virus vaccine and a few facts
Tapasvi Puwar, Bhavna Puwar
July 2009, 63(7):309-310
DOI:10.4103/0019-5359.55116  PMID:19700913
  - 1,784 251
Linezolid vancomycin resistant Enterococcus isolated from clinical samples in Tehran hospitals
S Yasliani, A Mohabati Mobarez, R Hosseini Doust, M Satari, O Teymornejad
July 2009, 63(7):297-302
DOI:10.4103/0019-5359.55117  PMID:19700910
Background: Vancomycin-resistant enterococci pose an emerging health risk. The limitation in therapeutic options has resulted in the development of new drugs such as quinupristin/ dalfopristin and linezolid. Aim, Setting and Design: This study investigated the species prevalence and antibacterial resistance among enterococci isolated in selected Tehran hospitals. Materials and Methods: Between March 2006 and August 2007, 200 enterococcal isolates from urine, blood, stool and wound were recovered in 2 teaching hospitals of Tehran province. Susceptibility of all isolates was tested against vancomycin, teicoplanin and linezolid antibiotics by disk diffusion and agar dilution method. Results and Conclusion: Seventeen (8.5%), 6 (3%) and 4 (2%) of the isolates were resistant to vancomycin, teicoplanin and linezolid, respectively. Within the vancomycin-resistant isolates, 6 (35.2%), 4 (25%) and 1 (5.88%) showed vanA, vanB and vanC genotype patterns, respectively. Four (23.5%) of VRE isolates were resistant to linezolid with minimum inhibitory concentrations between 16 and 32 g/mL. Two linezolid vancomycin resistant enterococci were E. faecium.
  - 2,799 371
2004 - Indian Journal of Medical Sciences
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Online since 15th December '04