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Year : 2004  |  Volume : 58  |  Issue : 1  |  Page : 10--15

Bacteriological and antimicrobial susceptibility profile of soft tissue infections from Northern India

S Mohanty, Arti Kapil, B Dhawan, BK Das 
 Department of Microbiology, AIIMS, New Delhi - 110029, India

Correspondence Address:
Arti Kapil
Department of Microbiology, AIIMS, New Delhi - 110029
India

BACKGROUND: Soft tissue infections require a judicious combination of antimicrobial therapy in addition to surgical debridement to limit tissue loss and preserve life. AIMS: To study the bacterial etiology of soft tissue infections and their antimicrobial susceptibility pattern. Settings and design: A single institutional retrospective study of one year duration from January to December 2002. MATERIALS AND METHODS: A total of 5039 consecutive pus samples received in the Bacteriology Laboratory was analyzed from the records. RESULTS: There were a total of 2783 bacterial isolates comprising of 1504 gram negative bacilli and 1279 gram positive cocci. Staphylococcus aureus was the commonest isolate followed by Escherichia coli and Pseudomonas species. Methicillin resistance in S. aureus was found to be 38.56%, high level aminoglycoside resistance was observed in 53.3% enterococci and 66.75% of the gram negative bacilli were extended spectrum beta-lactamase producers. Rifampicin and vancomycin showed best activity for S. aureus; for gram-negative bacilli, piperacillin-tazobactam combination showed best activity. CONCLUSIONS: Continuous monitoring of antimicrobial susceptibility pattern in individual settings together with their judicious use is emphasized to minimize emergence of drug resistant bacteria.


How to cite this article:
Mohanty S, Kapil A, Dhawan B, Das B K. Bacteriological and antimicrobial susceptibility profile of soft tissue infections from Northern India.Indian J Med Sci 2004;58:10-15


How to cite this URL:
Mohanty S, Kapil A, Dhawan B, Das B K. Bacteriological and antimicrobial susceptibility profile of soft tissue infections from Northern India. Indian J Med Sci [serial online] 2004 [cited 2013 May 24 ];58:10-15
Available from: http://www.indianjmedsci.org/article.asp?issn=0019-5359;year=2004;volume=58;issue=1;spage=10;epage=15;aulast=Mohanty;type=0