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LETTER TO EDITOR
Year : 2009  |  Volume : 63  |  Issue : 2  |  Page : 81-82
 

Hypothyroid myopathy or rhabdomyolysis


Department of Medicine, University College of Medical Sciences and GTB Hospital, Delhi, India

Correspondence Address:
Vishal Sharma
19 Gobind Nagar Chheharta, Amritsar - 143 105
India
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DOI: 10.4103/0019-5359.49248

PMID: 19359774

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How to cite this article:
Sharma V, Sharma A, Aggarwal S. Hypothyroid myopathy or rhabdomyolysis. Indian J Med Sci 2009;63:81-2

How to cite this URL:
Sharma V, Sharma A, Aggarwal S. Hypothyroid myopathy or rhabdomyolysis. Indian J Med Sci [serial online] 2009 [cited 2013 May 18];63:81-2. Available from: http://www.indianjmedsci.org/text.asp?2009/63/2/81/49248


Sir,

The article "Hypothyroidism-associated rhabdomyolysis" was interesting. [1] The clinical description of the patient fits in with the diagnosis of hypothyroid myopathy. The serum creatinine value is practically normal (1.6 mg%), and the fact that the patient has a normal blood urea and a normal urine output indicates that the renal function is virtually normal. Rhabdomyolysis is a more severe illness which presents acutely with features of myalgias, hyperkalemia, renal dysfunction, metabolic acidosis and features of disseminated intravascular coagulation, apart from elevated creatinine kinase levels. Also, the serum creatinine kinase levels are about 5 times the normal, which is possible even in hypothyroid myopathy. Even levels up to 9000 have been reported. [2] All in all, the case appears to be more of a hypothyroid myopathy rather than a rhabdomyolysis.

The authors also mention that the patient has borderline first-degree heart block on EKG. In the setting of rhabdomyolysis, this should alert the clinician about the possibility of hyperkalemia secondary to muscle damage. The authors fail to mention the serum K+ levels and also whether the abnormality improved with treatment.

 
 ¤ References Top

1.Chowta MN, Chowta NK. Hypothyroidism-associated rhabdomyolysis. Indian J Med Sci 2008;62:496-7.  Back to cited text no. 1  [PUBMED]  Medknow Journal
2.Finsterer J, Stφllberger C, Grossegger C, Kroiss A. Hypothyroid myopathy with unusually high serum creatine kinase values. Horm Res 1999;52:205-8.   Back to cited text no. 2    




 

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