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Year : 1992  |  Volume : 46  |  Issue : 1  |  Page : 7-11

Changes in pulmonary diffusing capacity and blood gases in chronic obstructive lung diseases.

Industrial Toxicology Research Centre, Lucknow,

Correspondence Address:
S K Rastogi
Industrial Toxicology Research Centre, Lucknow

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Source of Support: None, Conflict of Interest: None

PMID: 1452227

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Pulmonary diffusing capacity (TLco) of 19 cases of chronic obstructive lung diseases (Chronic obstructive bronchitis and chronic obstructive emphysema) in the age group of 39 to 58 years (mean age: 49.8 +/- 5.5 SD years) are reported at rest in this investigation. The diffusing capacity for carbon monoxide (TLco) measured by standard methods was significantly reduced in all cases. The mean was 13.1 +/- 2.3 SD ml/min/mmHg. The blood gas findings revealed low arterial oxygen saturation (mean value: 90.2 +/- 2.2%). Arterial carbon dioxide tension was higher than in normal subjects. The mean for this series was 44.8 +/- 4.9 SD mmHg. The mean for normal subjects was 37.5 mmHg and the range 28.2 to 41.5.

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